Committee on Sanitary and Phytosanitary Measures - Notification - United States - Pesticides - Residues - Isocycloseram

NOTIFICATION

1.

Notifying Member: UNITED STATES OF AMERICA

If applicable, name of local government involved:

2.

Agency responsible: U.S. Environmental Protection Agency

3.

Products covered (provide tariff item number(s) as specified in national schedules deposited with the WTO; ICS numbers should be provided in addition, where applicable): Multiple commodities

4.

Regions or countries likely to be affected, to the extent relevant or practicable:

[X]     All trading partners

[ ]      Specific regions or countries:

5.

Title of the notified document: Isocycloseram; Pesticide Tolerances. Final rule. Language(s): English. Number of pages: 7

https://www.govinfo.gov/content/pkg/FR-2025-11-20/html/2025-20460.htm

6.

Description of content: This regulation establishes tolerances for residues of isocycloseram (CASRN 2061933-85-3) in or on multiple commodities.

7.

Objective and rationale: [X] food safety, [ ] animal health, [ ] plant protection, [ ] protect humans from animal/plant pest or disease, [ ] protect territory from other damage from pests.

8.

Is there a relevant international standard? If so, identify the standard:

[X]       Codex Alimentarius Commission (e.g. title or serial number of Codex standard or related text):

            The Codex pesticide reference number for isocycloseram is 334

[ ]        World Organization for Animal Health (OIE) (e.g. Terrestrial or Aquatic Animal Health Code, chapter number):

[ ]        International Plant Protection Convention (e.g. ISPM number):

[ ]        None

Does this proposed regulation conform to the relevant international standard?

[ ] Yes   [X] No

If no, describe, whenever possible, how and why it deviates from the international standard: The Codex has established MRLs for residues of isocycloseram in or on apple, wet pomace at 1 ppm; fruit, citrus, group 10-10, oil at 80 ppm; fruit, citrus, group 10-10, dried pulp at 3 ppm; and plum, prune, dried at 1.5 ppm. These MRLs are the same level as the tolerances being established for residues of isocycloseram in the United States.

The Codex has also established MRLs for residues of isocycloseram in or on cattle, meat at 0.02 ppm; goat, meat at 0.02 ppm; horse, meat at 0.02 ppm; milk at 0.05 ppm; poultry, meat at 0.02 ppm and sheep, meat at 0.02 ppm. These MRL levels are different than the tolerance levels being established for isocycloseram in the United States. The United Sates has established tolerances for each of the above-listed commodities at 0.01 ppm to ensure no potential trade barriers with key importing partners of U.S. meat (Korea) and milk (Mexico, Indonesia, Vietnam) products.

9.

Other relevant documents and language(s) in which these are available: https://www.regulations.gov/docket/EPA-HQ-OPP-2021-0641 (available in English)

10.

Proposed date of adoption (dd/mm/yy): 20 November 2025

Proposed date of publication (dd/mm/yy): 20 November 2025

11.

Proposed date of entry into force: [ ] Six months from date of publication, and/or (dd/mm/yy): 20 November 2025

[ ]      Trade facilitating measure

12.

Final date for comments: [ ] Sixty days from the date of circulation of the notification and/or (dd/mm/yy): Not applicable

Agency or authority designated to handle comments: [ ] National Notification Authority, [ ] National Enquiry Point. Address, fax number and e-mail address (if available) of other body:

Comments should be submitted to EPA's WTO SPS team at EPAWTOSPS@epa.gov.

13.

Text(s) available from: [ ] National Notification Authority, [ ] National Enquiry Point. Address, fax number and e-mail address (if available) of other body:

https://www.govinfo.gov/content/pkg/FR-2025-11-20/html/2025-20460.htm