Governments across different regions of the world have actively invested in initiatives that promote digital transformation to ensure nations’ digital autonomy, with the EU as one of the leaders. The recent disinformation war-fare undertaken by Russia as part of its invasion to Ukraine further underscores the threat to, and importance of digital autonomy. Based on both the EU and Taiwan’s efforts in promoting digital autonomy, this chapter offers several recommendations, including creating a systematic dialogue and information-sharing mechanism, as well as forging partnerships in R&D collaborations, talent development and data/privacy governance.